Coming from the pistil of a variety of crocuses, this most expensive spice in the world is nicknamed "red gold". Natural saffron is not used in perfumery because it contains safrol, a highly allergenic compound. But its effect is reproduced with one of its derivatives, saffronal. Its very powerful perfume is bitter and slightly metallic, blowing hot and cold on the rest of the composition with also a leathery, tarred facet. Francis Kurkdjian likes to use it in the top layer of a fragrance to break the sweetness of citrus notes. It is often associated with Oud-based perfumes and oriental amber accords.